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Vinegoni, C.* ; Razansky, D. ; Hilderbrand, S.A.* ; Shao, F.W.* ; Ntziachristos, V. ; Weissleder, R.*

Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles.

Opt. Lett. 34, 2566-2568 (2009)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
We report on a systematic study of upconverting fluorescence signal generation within turbid phantoms and real tissues. An accurate three-point Green's function, describing the forward model of photon propagation, is established and experimentally validated. We further demonstrate, for the first time to our knowledge, autofluorescence-free transillumination imaging of mice that have received biocompatible upconverting nanoparticles. The method holds great promise for artifact-free whole-body visualization of optical molecular probes.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0146-9592
e-ISSN 1539-4794
Journal Optics Letters
Quellenangaben Volume: 34, Issue: 17, Pages: 2566-2568 Article Number: , Supplement: ,
Publisher Optical Society of America (OSA)
Non-patent literature Publications
Reviewing status Peer reviewed