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Open Access Green as soon as Postprint is submitted to ZB.
Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles.
Opt. Lett. 34, 2566-2568 (2009)
We report on a systematic study of upconverting fluorescence signal generation within turbid
phantoms and real tissues. An accurate three-point Green's function, describing the forward model
of photon propagation, is established and experimentally validated. We further demonstrate, for the
first time to our knowledge, autofluorescence-free transillumination imaging of mice that have
received biocompatible upconverting nanoparticles. The method holds great promise for artifact-free
whole-body visualization of optical molecular probes.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2009
HGF-reported in Year
0
ISSN (print) / ISBN
0146-9592
e-ISSN
1539-4794
Journal
Optics Letters
Quellenangaben
Volume: 34,
Issue: 17,
Pages: 2566-2568
Publisher
Optical Society of America (OSA)
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-505500-001
Erfassungsdatum
2009-12-31