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Felix, J. ; Becker, C. ; Vogl, M. ; Buschner, P.* ; Plötz, W.* ; Leidl, R.

Patient characteristics and valuation changes impact quality of life and satisfaction in total knee arthroplasty results from a German prospective cohort study.

Health Qual. Life Outcomes 17:180 (2019)
Publ. Version/Full Text DOI PMC
Open Access Gold
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Background: Evaluation of variations in pre- and postoperative patient reported outcomes (PRO) and the association between preoperative patient characteristics and health and satisfaction outcomes after total knee arthroplasty (TKA) may support shared decision-making in Germany. Since previous research on TKA health outcomes indicated valuation differences in longitudinal data, experienced-based population weights were used for the first time as an external valuation system to measure discrepancies between patient and average population valuation of HRQoL.Methods: Baseline data (n = 203) included sociodemographic and clinical characteristics and PROs, measured by the EQ-5D-3 L and WOMAC. Six-month follow-up data (n = 161) included medical changes since hospital discharge, PROs and satisfaction. A multivariate linear regression analysis was performed to evaluate the relationship between preoperative patient characteristics and PRO scores. Patient acceptable symptom state (PASS) was calculated to provide a satisfaction threshold. Patient-reported health-related quality of life (HRQoL) valuations were compared with average experienced-based population values to detect changes in valuation.Results: One hundred thirty-seven subjects met inclusion criteria. All PRO measures improved significantly. Preoperative WOMAC and EQ-5D VAS, housing situation, marital status, age and asthma were found to be predictors of postoperative outcomes. 73% of study participants valued their preoperative HRQoL higher than the general population valuation, indicating response shift. Preoperatively, patient-reported EQ-5D VAS was substantially higher than average experienced-based population values. Postoperatively, this difference declined sharply. Approximately 61% of the patients reported satisfactory postoperative health, being mainly satisfied with results if postoperative WOMAC was >= 82.49 (change >= 20.25) and postoperative EQ-5D VAS was >= 75 (change >= 6).Conclusion: On average, patients benefited from TKA. Preoperative WOMAC and EQ-5D VAS were predictors of postoperative outcomes after TKA. Particularly patients with high absolute preoperative PRO scores were more likely to remain unsatisfied. Therefore, outcome prediction can contribute to shared-decision making. Using general population valuations as a reference, this study underlined a discrepancy between population and patient valuation of HRQoL before, but not after surgery, thus indicating a potential temporary response shift before surgery.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Germany ; Total Knee Arthroplasty ; Preoperative Patient Characteristics ; Health-related Quality Of Life ; Satisfaction ; Response Shift ; External Valuation; Reported Outcome Measures; Detect Response Shifts; Total Hip-replacement; Functional Outcomes; Joint Arthroplasty; True Change; Osteoarthritis; Surgery; States; Womac
ISSN (print) / ISBN 1477-7525
e-ISSN 1477-7525
Quellenangaben Volume: 17, Issue: 1, Pages: , Article Number: 180 Supplement: ,
Publisher BioMed Central
Publishing Place Campus, 4 Crinan St, London N1 9xw, England
Non-patent literature Publications
Reviewing status Peer reviewed