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Open Access Green as soon as Postprint is submitted to ZB.
Iterative finite-element-based inversion for quantified detection of molecular targets using optoacoustic tomography.
Proc. SPIE 7258, (Suppl.1) :725812 (2009)
We describe an improved optoacoustic tomography method, that utilizes a diffusion-based photon propagation model in order to obtain quantified reconstruction of targets embedded deep in heterogeneous scattering and absorbing tissue. For the correction we utilize an iterative finite-element solution of the light diffusion equation to build a photon propagation model. We demonstrate image improvements achieved by this method by using tissue-mimicking phantom measurements. The particular strength of the method is its ability to achieve quantified reconstructions in non-uniform illumination configurations resembling whole-body small animal imaging scenarios.
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Publication type
Article: Journal article
Document type
Scientific Article
Editors
Ehsan, S.* ; Jiang, H.*
Keywords
Finite Element Methods ; Iterative Methods ; Normalization Methods ; Optoacoustics ; Tomographic Imaging
ISSN (print) / ISBN
0277-786X
e-ISSN
1996-756X
Journal
Proceedings of SPIE
Quellenangaben
Volume: 7258,
Article Number: 725812,
Supplement: (Suppl.1)
Series
Proceedings of SPIE
Publisher
SPIE
Publishing Place
Bellingham, WA
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)