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Open Access Green as soon as Postprint is submitted to ZB.
Genome-wide association scans for Type 2 diabetes: New insights into biology and therapy.
Trends Pharmacol. Sci. 28, 598-601 (2007)
Type 2 diabetes is a complex, multifactorial disease, for which genetic and environmental factors jointly determine susceptibility. Disentangling the genetic aetiology of Type 2 diabetes has proven a challenging task, rewarded, until recently, with only limited success. However, the field of Type 2 diabetes genetics has been transformed over the past few months, with the publication of six genome-wide association scans, leading to the establishment of novel genomic regions that harbour disease susceptibility loci. Here, we provide an overview of the main recent findings and discuss their significance in providing biological insights and their translational implications.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0165-6147
e-ISSN
1873-3735
Quellenangaben
Volume: 28,
Issue: 12,
Pages: 598-601
Publisher
Cell Press
Publishing Place
Amsterdam
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Translational Genomics (ITG)