PuSH - Publication Server of Helmholtz Zentrum München

Continuous acquisition scanner for whole-body multispectral optoacoustic tomography.

Proc. SPIE 7564:756429 (2010)
Publ. Version/Full Text DOI
Open Access Green as soon as Postprint is submitted to ZB.
An essential problem dealing with three-dimensional optoacoustic imaging is the long data acquisition times associated with recording signals from multiple spatial projections, where signal averaging for each projection is applied to obtain satisfying signal-to-noise-ratio. This approach complicates acquisition and makes imaging challenging for most applications, especially for in vivo imaging and multispectral imaging. Instead we employ a herein introduced continuous data acquisition methodology that greatly shortens recording times over multiple projection angles and acquires high quality tomographic data without averaging. By this means a two dimensional image acquisition having 270 angular projections only takes about 9 seconds, while a full multispectral three dimensional image can normally take about 15 minutes to acquire with a single ultrasonic detector. The system performance is verified on tissue-mimicking phantoms containing known concentrations of fluorescent molecular agent as well as small animals.
Altmetric
Additional Metrics?
Edit extra informations Login
Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Photoacoustic imaging; Biomedical Optics; Multispectral and hyperspectral imaging; Medical and biological imaging; Medical optics instrumentation
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Quellenangaben Volume: 7564, Issue: , Pages: , Article Number: 756429 Supplement: ,
Publisher SPIE
Publishing Place Bellingham, WA
Non-patent literature Publications
Reviewing status Peer reviewed