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Continuous acquisition scanner for whole-body multispectral optoacoustic tomography.
Proc. SPIE 7564:756429 (2010)
Publ. Version/Full Text
DOI
An essential problem dealing with three-dimensional optoacoustic imaging is the long data acquisition times associated with recording signals from multiple spatial projections, where signal averaging for each projection is applied to obtain satisfying signal-to-noise-ratio. This approach complicates acquisition and makes imaging challenging for most applications, especially for in vivo imaging and multispectral imaging. Instead we employ a herein introduced continuous data acquisition methodology that greatly shortens recording times over multiple projection angles and acquires high quality tomographic data without averaging. By this means a two dimensional image acquisition having 270 angular projections only takes about 9 seconds, while a full multispectral three dimensional image can normally take about 15 minutes to acquire with a single ultrasonic detector. The system performance is verified on tissue-mimicking phantoms containing known concentrations of fluorescent molecular agent as well as small animals.
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Publication type
Article: Journal article
Document type
Scientific Article
Editors
Oraevsky, A. A.* ; Wang, L.V.*
Keywords
Photoacoustic imaging; Biomedical Optics; Multispectral and hyperspectral imaging; Medical and biological imaging; Medical optics instrumentation
Language
english
Publication Year
2010
HGF-reported in Year
0
ISSN (print) / ISBN
0277-786X
e-ISSN
1996-756X
Journal
Proceedings of SPIE
Quellenangaben
Volume: 7564,
Article Number: 756429
Publisher
SPIE
Publishing Place
Bellingham, WA
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-505500-001
Erfassungsdatum
2010-07-21