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Jaeschke, L.* ; Steinbrecher, A.* ; Greiser, K.H.* ; Dörr, M.* ; Buck, T.* ; Linseisen, J. ; Meisinger, C. ; Ahrens, W.* ; Becher, H.* ; Berger, K.* ; Braun, B.* ; Brenner, H.* ; Castell, S.* ; Fischer, B.* ; Franzke, C.W.* ; Gastell, S.* ; Günther, K.* ; Hoffmann, W.* ; Holleczek, B.* ; Jagodzinski, A.* ; Kaaks, R.* ; Kluttig, A.* ; Krause, G.* ; Krist, L.* ; Kuß, O.* ; Lehnich, A.T.* ; Leitzmann, M.* ; Lieb, W.* ; Löffler, M.* ; Michels, K.B.* ; Mikolajczyk, R.* ; Peters, A. ; Schikowski, T.* ; Schipf, S.* ; Schmidt, B.* ; Schulze, M.* ; Völzke, H.* ; Willich, S.N.* ; Pischon, T.*

Erfassung selbst berichteter kardiovaskulärer und metabolischer Erkrankungen in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse.

Assessment of self-reported cardiovascular and metabolic diseases in the German National Cohort (GNC, NAKO Gesundheitsstudie): Methods and initial results.

Bundesgesundheitsbl.-Gesund. 63, 439-451 (2020)

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Background Data on self-reported cardiovascular and metabolic diseases are available for the first 100,000 participants of the population-based German National Cohort (GNC, NAKO Gesundheitsstudie). Objectives To describe assessment methods and the frequency of self-reported cardiovascular and metabolic diseases in the German National Cohort. Materials and methods Using a computer-based, standardized personal interview, 101,806 participants (20-75 years, 46% men) from 18 nationwide study centres were asked to use a predefined list to report medical conditions ever diagnosed by a physician, including cardiovascular or metabolic diseases. For the latter, we calculated sex-stratified relative frequencies and compared these with reference data. Results With regard to cardiovascular diseases, 3.5% of men and 0.8% of women reported to have ever been diagnosed with a myocardial infarction, 4.8% and 1.5% with angina pectoris, 3.5% and 2.5% with heart failure, 10.1% and 10.4% with cardiac arrhythmia, 2.7% and 1.8% with claudicatio intermittens, and 34.6% and 27.0% with arterial hypertension. The frequencies of self-reported diagnosed metabolic diseases were 8.1% and 5.8% for diabetes mellitus, 28.6% and 24.5% for hyperlipidaemia, 7.9% and 2.4% for gout, and 10.1% and 34.3% for thyroid diseases. Observed disease frequencies were lower than reference data for Germany. Conclusions In the German National Cohort, self-reported cardiovascular and metabolic diseases diagnosed by a physician are assessed from all participants, therefore representing a data source for future cardio-metabolic research in this cohort.

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