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Hassenstein, M.J.* ; Aarabi, G.* ; Ahnert, P.* ; Becher, H.* ; Franzke, C.W.* ; Fricke, J.* ; Krause, G.* ; Glöckner, S.* ; Gottschick, C.* ; Karch, A.* ; Kemmling, Y.* ; Kerrinnes, T.* ; Lange, B.* ; Mikolajczyk, R.* ; Nieters, A.* ; Ott, J.J.* ; Ahrens, W.* ; Berger, K.* ; Meinke-Franze, C.* ; Gastell, S.* ; Günther, K.* ; Greiser, K.H.* ; Holleczek, B.* ; Horn, J.* ; Jaeschke, L.* ; Jagodzinski, A.* ; Jansen, L.* ; Jochem, C.* ; Jöckel, K.H.* ; Kaaks, R.* ; Krist, L.* ; Kuß, O.* ; Langer, S.* ; Legath, N.* ; Leitzmann, M.* ; Lieb, W.* ; Loeffler, M.* ; Mangold, N. ; Michels, K.B.* ; Meisinger, C. ; Obi, N.* ; Pischon, T.* ; Schikowski, T.* ; Schipf, S.* ; Schulze, M.B.* ; Stang, A.* ; Waniek, S.* ; Wirkner, K.* ; Willich, S.N.* ; Castell, S.*

Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape.

Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape.

Bundesgesundheitsbl.-Gesund. 63, 404-414 (2020)
Postprint Research data DOI PMC
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Background: Infectious diseases continue to play an important role for disease perception, health-economic considerations and public health in Germany. In recent years, infectious diseases have been linked to the development of non-communicable diseases. Analyses of the German National Cohort (GNC) may provide deeper insights into this issue and pave the way for new targeted approaches in disease prevention. Objectives: The aim was to describe the tools used to assess infectious diseases and to present initial data on infectious disease frequencies, as well as to relate the GNC assessment tools to data collection methods in other studies in Germany. Methods: As part of the baseline examination, questions regarding infectious diseases were administered using both an interview and a self-administered touchscreen questionnaire. Data from the initial 101,787 GNC participants were analysed. Results: In the interview, 0.2% (HIV/AIDS) to 8.6% (shingles) of respondents reported ever having a medical diagnosis of shingles, postherpetic neuralgia (in cases where shingles was reported), hepatitis B/C, HIV/AIDS, tuberculosis or sepsis if treated in hospital. In the questionnaire, 12% (cystitis) to 81% (upper respiratory tract infections) of respondents reported having experienced at least one occurrence of upper or lower respiratory tract infections, gastrointestinal infections, cystitis or fever within the past 12 months. Outlook: The cross-sectional analyses of data and tools presented here – for example on determinants of susceptibility to self-reported infections – can be anticipated from the year 2021 onward. Beyond that, more extensive research into infectious disease epidemiology will follow, particularly once analyses of GNC biological materials have been performed.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Cohort Study ; Communicable Diseases ; Epidemiology ; German National Cohort (gnc) ; Infectious Disease Epidemiology ; Infectious Diseases; Urinary-tract-infection; Herpes-zoster; Disease Burden; Global Burden; Hepatitis-b; Health; Risk; Questionnaire; Prevalence; Pneumonia
ISSN (print) / ISBN 1436-9990
e-ISSN 1437-1588
Journal Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz
Quellenangaben Volume: 63, Issue: 4, Pages: 404-414 Article Number: , Supplement: ,
Publisher Springer
Publishing Place One New York Plaza, Suite 4600, New York, Ny, United States
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology II (EPI2)
Independent Research Group Clinical Epidemiology (KEPI)