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Nutrition and the immune system: A complicated tango.
Nutrients 12:818 (2020)
Enthusiasm exists for the potential of diet to impact the immune system, prevent disease and its therapeutic potential. Herein, we describe the challenge to nutrition scientists in defining this relationship through case studies of diets and nutrients in the context of allergic and autoimmune diseases. Moderate-quality evidence exists from both human intervention and observational studies to suggest that diet and individual nutrients can influence systemic markers of immune function and inflammation; numerous challenges exist for demonstrating the impact of defined diets and nutrient interventions on clearly influencing immune-mediated-clinical disease endpoints. A growing body of evidence suggests that further consideration of dietary patterns, immune system and gut microbiome composition and function, and subsequent epigenetic modifications are needed to improve our understanding of diet-immune system interactions.
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Publication type
Article: Journal article
Document type
Review
Keywords
Nutrition ; Omega-3 Fatty Acids ; Fiber ; Immune System ; Microbiome; Polyunsaturated Fatty-acids; Gut Microbiota Composition; Food Allergy; Mediterranean Diet; Barrier Function; Rheumatoid-arthritis; Primary Prevention; Cardiovascular-disease; Clinical-trial; Fish-oil
ISSN (print) / ISBN
2072-6643
e-ISSN
2072-6643
Journal
Nutrients
Quellenangaben
Volume: 12,
Issue: 3,
Article Number: 818
Publisher
MDPI
Publishing Place
Basel
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute for Allergy Research (IAF)