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Krššák, M.* ; Lindeboom, L.* ; Schrauwen-Hinderling, V.* ; Szczepaniak, L.S.* ; Derave, W.* ; Lundbom, J.* ; Befroy, D.* ; Schick, F.* ; Machann, J. ; Kreis, R.* ; Boesch, C.*

Proton magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations.

NMR Biomed.:e4266 (2021)
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1H-MR spectroscopy of skeletal muscle provides insight into metabolism that is not available noninvasively by other methods. The recommendations given in this article are intended to guide those who have basic experience in general MRS to the special application of 1H-MRS in skeletal muscle. The highly organized structure of skeletal muscle leads to effects that change spectral features far beyond simple peak heights, depending on the type and orientation of the muscle. Specific recommendations are given for the acquisition of three particular metabolites (intramyocellular lipids, carnosine and acetylcarnitine) and for preconditioning of experiments and instructions to study volunteers.
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Publication type Article: Journal article
Document type Review
Keywords Acetylacarnitine ; Carnosine ; Deoxymyoglobine ; Intramyocellular Lipids ; Lactate ; Magnetic Resonance Spectroscopy ; Physiology ; Skeletal Muscle
Language english
Publication Year 2021
Prepublished in Year 2020
HGF-reported in Year 2020
ISSN (print) / ISBN 0952-3480
e-ISSN 1099-1492
Journal NMR in Biomedicine
Quellenangaben Volume: , Issue: , Pages: , Article Number: e4266 Supplement: ,
Publisher Wiley
Reviewing status Peer reviewed
Institute(s) Institute of Diabetes Research and Metabolic Diseases (IDM)
POF-Topic(s) 90000 - German Center for Diabetes Research
Research field(s) Helmholtz Diabetes Center
PSP Element(s) G-502400-001
DOI 10.1002/nbm.4266
WOS ID WOS:000511037400001
Scopus ID 85079160122
PubMed ID 32022964
Erfassungsdatum 2020-04-08
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