PuSH - Publication Server of Helmholtz Zentrum München

Siehler, J. ; Blöchinger, A. ; Lickert, H.

Pharmacological targeting of the actin cytoskeleton to drive endocrinogenesis.

Trends Pharmacol. Sci. 41, 384-386 (2020)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
In vitro generation of insulin-secreting beta cells from human pluripotent stem cells (hPSCs) opens new avenues for treating and modeling diabetes. Hogrebe and colleagues established a new 2D differentiation protocol where they targeted the cytoskeleton pharmacologically for controlled endocrine induction and generation of hPSC-derived beta cells with improved function.
Altmetric
Additional Metrics?
[➜Log in]
Edit extra informations Login
Publication type Article: Journal article
Document type Other: Opinion
Corresponding Author
Keywords Actin ; Beta Cells ; Endocrine Progenitors ; Latrunculin A ; Pancreatic Progenitors ; Stem Cells; Beta-cells; In-vitro
ISSN (print) / ISBN 0165-6147
e-ISSN 1873-3735
Journal Trends in Pharmacological Sciences
Quellenangaben Volume: 41, Issue: 6, Pages: 384-386 Article Number: , Supplement: ,
Publisher Cell Press
Publishing Place Amsterdam
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Diabetes and Regeneration Research (IDR)