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Voigt, K. ; Brüggemann, R.* ; Scherb, H. ; Shen, H. ; Schramm, K.-W.

Evaluating the relationship between chemical exposure and cryptorchidism.

Environ. Modell. Softw. 25, 1801-1812 (2010)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
One method for the evaluation of complex environmental and health datasets is the discrete mathematical method Hasse diagram technique based on partial orders. The introduced software program package is named PyHasse. In this paper we evaluate a possible human association between maternal exposure to organochlorine compounds used as pesticides and cryptorchidism among male children in Finland and Denmark. We identified differences in comparable and incomparable objects and quantified these differences by the software tool Similarity Analysis in the program PyHasse. Furthermore we interpreted the corresponding Hasse diagrams concerning chosen “striking objects”. We found the position of the chemicals AHCH (alpha-Hexachlorohexane), CHCE (cis-Heptachloroepoxide), DIEL (Dieldrin), and MIRE (Mirex) has some influence on the differentiation of the Hasse diagrams and hence of each two datasets analyzed. The largest disparities can be observed when we compare the Finnish and Danish datasets concerning cryptorchidism. The disparities are demonstrated in the corresponding Hasse diagrams.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Environmental health data; Cryptorchidism; HASSE diagram technique; Partially ordered sets; Environmental software; PyHasse
ISSN (print) / ISBN 1364-8152
e-ISSN 1873-6726
Quellenangaben Volume: 25, Issue: 12, Pages: 1801-1812 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Oxford
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Biomathematics and Biometry (IBB)
Institute of Ecological Chemistry (IOEC)