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Evaluating the relationship between chemical exposure and cryptorchidism.
Environ. Modell. Softw. 25, 1801-1812 (2010)
One method for the evaluation of complex environmental and health datasets is the discrete mathematical method Hasse diagram technique based on partial orders. The introduced software program package is named PyHasse. In this paper we evaluate a possible human association between maternal exposure to organochlorine compounds used as pesticides and cryptorchidism among male children in Finland and Denmark. We identified differences in comparable and incomparable objects and quantified these differences by the software tool Similarity Analysis in the program PyHasse. Furthermore we interpreted the corresponding Hasse diagrams concerning chosen “striking objects”. We found the position of the chemicals AHCH (alpha-Hexachlorohexane), CHCE (cis-Heptachloroepoxide), DIEL (Dieldrin), and MIRE (Mirex) has some influence on the differentiation of the Hasse diagrams and hence of each two datasets analyzed. The largest disparities can be observed when we compare the Finnish and Danish datasets concerning cryptorchidism. The disparities are demonstrated in the corresponding Hasse diagrams.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Environmental health data; Cryptorchidism; HASSE diagram technique; Partially ordered sets; Environmental software; PyHasse
ISSN (print) / ISBN
1364-8152
e-ISSN
1873-6726
Quellenangaben
Volume: 25,
Issue: 12,
Pages: 1801-1812
Publisher
Elsevier
Publishing Place
Oxford
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biomathematics and Biometry (IBB)
Institute of Ecological Chemistry (IOEC)
Institute of Ecological Chemistry (IOEC)