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Cost-effectiveness of diagnostic interventions: Non-small cell lung cancer.

Onkologe 16, 992-1002 (2010)
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Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
The present article is intended as an introduction to health economic evaluation as well as a review of economic evaluations of positron emission tomography (PET and PET/CT) in the diagnosis and management of non-small cell lung cancer. Furthermore, the transferability of the results of economic evaluations in other countries to the German health care context is assessed. With the help of a literature search 13 full health economic evaluations of staging (12 studies) and follow-up (1 study) of non-small cell lung cancer were identified. The primary health benefit measure was life years gained or quality-adjusted life years gained. All of these evaluations were based on modeling studies. Due to differences in assumptions and methodological heterogeneity, the incremental cost-effectiveness ratios varied widely. Because of the complexity of the diagnostic and therapeutic process, the transferability of international study results to the German situation is limited. The cost-effectiveness of PET for other management decisions in non-small cell lung cancer (e.g. radiotherapy planning) is still to be assessed.
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Publication type Article: Journal article
Document type Scientific Article
Keywords 18F-Fluorodeoxyglucose; Positron-emission tomography; Computed tomography; Non-small cell lung cancer; Cost effectiveness; POSITRON-EMISSION-TOMOGRAPHY; FDG-PET; TECHNOLOGY-ASSESSMENT; PATIENT-MANAGEMENT; IMPACT; CARCINOMA; ONCOLOGY; RECOMMENDATIONS; ACCURACY; STRATEGY
Language german
Publication Year 2010
HGF-reported in Year 2010
ISSN (print) / ISBN 0947-8965
e-ISSN 1433-0415
Journal Onkologe, Der
Quellenangaben Volume: 16, Issue: 10, Pages: 992-1002 Article Number: , Supplement: ,
Publisher Springer
Publishing Place New York
Reviewing status Peer reviewed
POF-Topic(s) 30202 - Environmental Health
Research field(s) Genetics and Epidemiology
PSP Element(s) G-505300-001
Scopus ID 78349304664
Erfassungsdatum 2010-12-06