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Mitochondrial ejection for cardiac protection: The Macrophage Connection.
Cell Metab. 32, 512-513 (2020)
Publ. Version/Full Text
DOI
PMC
Mitochondrial dysfunction is a hallmark of heart disease. Nicolas-Avila et al. (2020) now find that cardiomyocytes eject dysfunctional mitochondria in exopher vesicles, which require elimination by specialized heart-resident macrophages, altogether supporting proper heart function.
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Publication type
Article: Journal article
Document type
Other: Opinion
ISSN (print) / ISBN
1550-4131
e-ISSN
1932-7420
Journal
Cell Metabolism
Quellenangaben
Volume: 32,
Issue: 4,
Pages: 512-513
Publisher
Elsevier
Publishing Place
50 Hampshire St, Floor 5, Cambridge, Ma 02139 Usa
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Cancer (IDC)
Grants
European Research Council (ERC)
German Centre for Cardiovascular Research (DZHK)
Deutsche Forschungsgemeinschaft
German Centre for Cardiovascular Research (DZHK)
Deutsche Forschungsgemeinschaft