PuSH - Publication Server of Helmholtz Zentrum München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Greulich, F. ; Wierer, M.* ; Mechtidou, A. ; Gonzalez-Garcia, O. ; Uhlenhaut, N.H.

The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers.

Cell Rep. 34:108742 (2021)
Publ. Version/Full Text Research data DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
The Authors Glucocorticoids such as dexamethasone are widely used immunomodulators. Combining proteomics, ChIP-seq, RNA-seq, and genetic loss-of-function studies in murine macrophages, Greulich et al. show that recruitment of the SETD1A/COMPASS complex to cis-regulatory elements by the glucocorticoid receptor mediates some of their anti-inflammatory actions.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
9.423
1.943
4
5
Tags
Annotations
Special Publikation
Hide on homepage

Edit extra information
Edit own tags
Private
Edit own annotation
Private
Hide on publication lists
on hompage
Mark as special
publikation
Publication type Article: Journal article
Document type Scientific Article
Keywords Compass Complex ; Dexamethasone ; Enhancers ; Genomics ; Glucocorticoid Receptor ; H3k4 Methylation ; Inflammation ; Macrophages ; Setd1a ; Transcription; Histone H3; Binding Protein; Methyltransferase Complex; Saccharomyces-cerevisiae; Chromatin Accessibility; Molecular Regulation; Set1 Complex; Phd Finger; R Package; Gene
Language english
Publication Year 2021
HGF-reported in Year 2021
ISSN (print) / ISBN 2211-1247
e-ISSN 2211-1247
Journal Cell Reports
Quellenangaben Volume: 34, Issue: 6, Pages: , Article Number: 108742 Supplement: ,
Publisher Cell Press
Publishing Place 50 Hampshire St, Floor 5, Cambridge, Ma 02139 Usa
Reviewing status Peer reviewed
Institute(s) Institute of Diabetes and Cancer (IDC)
POF-Topic(s) 90000 - German Center for Diabetes Research
Research field(s) Helmholtz Diabetes Center
PSP Element(s) G-501900-227
Grants ERC
DFG
DOI 10.1016/j.celrep.2021.108742
WOS ID WOS:000617458200016
Scopus ID 85100505103
PubMed ID 33567280
Erfassungsdatum 2021-04-14
[➜Report correction]