PuSH - Publication Server of Helmholtz Zentrum München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Koch, B.* ; Schäper, C.* ; Ewert, R.* ; Völzke, H.* ; Obst, A.* ; Friedrich, N.* ; Felix, S.B.* ; Vogelmeier, C.F.* ; Schnabel, E. ; Karrasch, S. ; Wichmann, H.-E. ; Schäfer, T.* ; Schulz, S. ; Heinrich, J. ; Gläser, S.*

Lung function reference values in different German populations.

Respir. Med. 105, 352-362 (2011)
Publ. Version/Full Text DOI PMC
Closed
Open Access Green as soon as Postprint is submitted to ZB.
Spirometry is a frequently performed lung function test and an important tool in medical surveillance examinations of pulmonary diseases. The interpretation of lung function relies on the comparison to reference values derived from a healthy population. The study aim was to compare the lung function data of three representative population-based German studies (Study of Health in Pomerania [SHIP-1], Cooperative Health Research in the Region of Augsburg [KORA-S3] and European Community Respiratory Health Survey Erfurt [ECRHS-I Erfurt]) with existing European spirometry reference values and to establish a new set of comprehensive German prediction equations. METHODS:Spirometry was performed in 4133 participants of three population-based surveys using almost identical standardised methods. Current and former smokers, subjects with cardiopulmonary disorders or on medication with potential influence on lung function were excluded. Sex specific prediction equations were established by quantile regression analyses. Comparison was performed to existing European reference values. RESULTS: The healthy reference sample consisted of 1302 (516 male) individuals, aged 20-80 years. Sex specific comprehensive prediction equations adjusted for age and height are provided. Significant differences were found in comparison to previous studies with pronounced lower values of the current population if applying historic prediction equations. CONCLUSION: The results contribute to the interpretation of lung function examination in providing a comprehensive set of spirometry reference values obtained in a large number of healthy volunteers. Whereas the differences in between the investigated studies are negligible, striking divergence was detected in comparison to historic and recent European spirometry prediction values.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
2.525
1.161
10
18
Tags
Annotations
Special Publikation
Hide on homepage

Edit extra information
Edit own tags
Private
Edit own annotation
Private
Hide on publication lists
on hompage
Mark as special
publikation
Publication type Article: Journal article
Document type Scientific Article
Keywords Reference values; Lung function; Prediction equations
Language
Publication Year 2011
HGF-reported in Year 2011
ISSN (print) / ISBN 0954-6111
e-ISSN 1532-3064
Journal Respiratory Medicine
Quellenangaben Volume: 105, Issue: 3, Pages: 352-362 Article Number: , Supplement: ,
Publisher Elsevier
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology (EPI)
POF-Topic(s) 30503 - Chronic Diseases of the Lung and Allergies
30202 - Environmental Health
Research field(s) Genetics and Epidemiology
PSP Element(s) G-503900-001
G-504090-001
DOI 10.1016/j.rmed.2010.10.014
Scopus ID 79151483777
PubMed ID 21130637
Erfassungsdatum 2011-05-17
[➜Report correction]