PuSH - Publication Server of Helmholtz Zentrum München: R spider: A network-based analysis of gene lists by combining signaling and metabolic pathways from Reactome and KEGG databases.

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Antonov, A.V. ; Schmidt, E.E.* ; Dietmann, S. ; Krestyaninova, M.* ; Hermjakob, H.*

R spider: A network-based analysis of gene lists by combining signaling and metabolic pathways from Reactome and KEGG databases.

Nucleic Acids Res. 38, 2, W78-W83 (2010)

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R spider is a web-based tool for the analysis of a gene list using the systematic knowledge of core pathways and reactions in human biology accumulated in the Reactome and KEGG databases. R spider implements a network-based statistical framework, which provides a global understanding of gene relations in the supplied gene list, and fully exploits the Reactome and KEGG knowledge bases. R spider provides a user-friendly dialog-driven web interface for several model organisms and supports most available gene identifiers. R spider is freely available at http://mips.helmholtz-muenchen.de/proj/rspider.

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