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Steckling-Muschack, N.* ; Mertes, H.* ; Mittermeier, I.* ; Schutzmeier, P.* ; Becker, J. ; Bergmann, K.C.* ; Böse-O′Reilly, S.* ; Buters, J.T.M. ; Damialis, A. ; Heinrich, J.* ; Kabesch, M.* ; Nowak, D.* ; Walser-Reichenbach, S.M.* ; Weinberger, A.* ; Zamfir, M.* ; Herr, C.* ; Kutzora, S.* ; Heinze, S.*

A systematic review of threshold values of pollen concentrations for symptoms of allergy.

Aerobiologia 37, 395–424 (2021)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
Pollen threshold values used in public warning systems are intended to inform people of the risk of developing allergy symptoms. However, there is no consensus about which pollen concentrations provoke allergy symptoms. The aim of this systematic review was the evaluation of studies investigating the relationship between pollen concentrations (alder, ash, birch, hazel, mugwort and ragweed) and the number of cases in which participants visited a doctor, drug consumption and allergy symptoms. This systematic literature review is registered in PROSPERO (CRD42019112369). A PubMed search was applied and enriched by consultation with experts and a snowball strategy. The included studies were checked for risk of bias (RoB), and extensive data were extracted and compared. Of 511 studies, 22 were eligible according to the previously established inclusion criteria, and 17 from these showed a low RoB. The strongest evidence was reported for ash (Fraxinus) pollen, where an increase of number of doctor’s visits at an interquartile range (IQR) of 18–28 grains/m was detected by three studies. Five studies about birch (Betula) pollen showed a threshold value of 45 grains/m for increased drug consumption. The evidence of a threshold value was limited for alder (Alnus), hazel (Corylus), mugwort (Artemisia) and ragweed (Ambrosia) pollen. The inconsistent results concerning all types of pollen, except ash pollen, can be the result of multiple factors, e.g., age, gender, allergen content of pollen and individual sensitivity. These influencing factors should be investigated more closely in future research.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Aeroallergens ; Conjunctivitis ; Pollen ; Pollen Thresholds ; Rhinitis ; Systematic Review; Emergency-department Visits; Outdoor Air-pollution; Bet V 1; Airborne Pollen; Clinical Symptoms; Drug Consumption; Birch Pollen; Asthma; Exposure; Rhinitis
Language english
Publication Year 2021
HGF-reported in Year 2021
ISSN (print) / ISBN 0393-5965
e-ISSN 1573-3025
Journal Aerobiologia
Quellenangaben Volume: 37, Issue: , Pages: 395–424 Article Number: , Supplement: ,
Publisher Pitagora Ed.
Publishing Place Bologna
Reviewing status Peer reviewed
Institute(s) Institute of Health Economics and Health Care Management (IGM)
Institute for Allergy Research (IAF)
Institute of Environmental Medicine (IEM)
POF-Topic(s) 30202 - Environmental Health
Research field(s) Genetics and Epidemiology
Allergy
PSP Element(s) G-505300-001
G-505400-001
G-503400-001
Grants Bavarian State Ministry of Health and Care
DOI 10.1007/s10453-021-09709-4
WOS ID WOS:000655536600002
Scopus ID 85106685967
Erfassungsdatum 2021-06-29
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