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Cutaneous barriers and skin immunity.
In:. Berlin ; Heidelberg: Springer, 2021. 43-52 (Handb. Exp. Pharmacol. ; 268)
The skin barrier provides us with several lines of protection from outside hazards. Its most outward layers, the stratum corneum and the epidermis seal our body with an acidic, dry, and rather cool surface, hostile to microbes. Yet, there are also fine-tuned interactions between the mostly commensal microbiota on top of the skin surface, with underlying epidermal cells as well as the immune system, to preserve a healthy steady state and to initiate repair processes when necessary. We take a concise look at the recent insights on the inner workings of this complex barrier.
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Publication type
Article: Edited volume or book chapter
Keywords
Immunity ; Microbiome ; Skin Barrier ; Staphylococcus
Language
english
Publication Year
2021
HGF-reported in Year
2021
ISSN (print) / ISBN
0171-2004
Quellenangaben
Volume: 268,
Pages: 43-52
Publisher
Springer
Publishing Place
Berlin ; Heidelberg
Reviewing status
Peer reviewed
Institute(s)
Institute for Allergy Research (IAF)
POF-Topic(s)
30202 - Environmental Health
Research field(s)
Allergy
PSP Element(s)
G-522200-001
Scopus ID
85119658279
PubMed ID
34114118
Erfassungsdatum
2021-07-19