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Ditz, B.* ; Boekhoudt, J.G.* ; Aliee, H. ; Theis, F.J. ; Nawijn, M.C.* ; Brandsma, C.A.* ; Hiemstra, P.S.* ; Timens, W.* ; Tew, G.W.* ; Grimbaldeston, M.A.* ; Neighbors, M.* ; Guryev, V.* ; van den Berge, M.* ; Faiz, A.*

Comparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: Does it provide new insights?

ERJ Open Res. 7:00104-2021 (2021)

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More DEGs are detected by RNA-Seq than microarrays in COPD lung biopsies and are associated with immunological pathways. Performing bulk tissue cell-type deconvolution in microarray lung samples, using the SVR method, reflects RNA-Seq results. https://bit.ly/2N8sY3s.

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Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

ISSN (print) / ISBN 2312-0541

e-ISSN 2312-0541

Journal ERJ Open Research

Quellenangaben Volume: 7, Issue: 2, Article Number: 00104-2021

Publisher European Respiratory Society

Publishing Place [S.l.]

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Computational Biology (ICB)