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Lafci, B.* ; Mercep, E. ; Herraiz, J.L.* ; Deán-Ben, X.L.* ; Razansky, D.

Transmission-reflection optoacoustic ultrasound (TROPUS) imaging of mammary tumors.

Proc. SPIE 11642:116422L (2021)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
Ultrasound (US) and optoacoustic (OA) imaging provide complementary information for quantitative analysis of the tumor microenvironment. Herein, we demonstrate the unique capabilities of transmission-reflection optoacoustic ultrasound (TROPUS) for characterizing breast cancer in tumor-bearing mice. For this, 4 different mice featuring orthotopic tumor of different sizes were scanned with a full-ring ultrasound transducer array to simultaneously render pulse-echo US images, speed of sound (SoS) maps and OA images. The tumor size, vascular density and its elastic parameters were further quantified in the images. Our results pave the way toward clinical translation of the hybrid TROPUS imaging for tumor detection and characterization.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Cancer Research ; Optoacoustic Imaging ; Photoacoustics ; Preclinical Imaging Of Tumors ; Speed Of Sound Imaging ; Ultrasound Computed Tomography
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Quellenangaben Volume: 11642, Issue: , Pages: , Article Number: 116422L Supplement: ,
Publisher SPIE
Non-patent literature Publications
Reviewing status Peer reviewed
Grants Deutsche Forschungsgemeinschaft (DFG German Research Foundation) Germany's Excellence Strategy