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Deconfining heterochromatin for expression.
Nat. Cell Biol. 23, 814-816 (2021)
Lineage-specific gene expression programs in multicellular organisms are controlled by balanced ON and OFF signals, amongst which heterochromatin regulates expression by restricting activation cues. A study now provides insights into mammalian heterochromatin organisation, function and interplay with lineage-specific transcription factors.
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Publication type
Article: Journal article
Document type
Other: Opinion
Keywords
Methylation; Enhancer
ISSN (print) / ISBN
1465-7392
e-ISSN
1476-4679
Journal
Nature Cell Biology
Quellenangaben
Volume: 23,
Issue: 8,
Pages: 814-816
Publisher
Nature Publishing Group
Publishing Place
Heidelberger Platz 3, Berlin, 14197, Germany
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Epigenetics and Stem Cells (IES)
Grants
Deutsche Forschungsgemeinschaft (German Research Foundation)
Helmholtz Association
Helmholtz Association