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Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
Current concepts and future perspectives on surgical optical imaging in cancer.
J. Biomed. Opt. 15:066024 (2010)
There are vibrant developments of optical imaging systems and contrast-enhancing methods that are geared to enhancing surgical vision and the outcome of surgical procedures. Such optical technologies designed for intraoperative use can offer high integration in the operating room compared to conventional radiological modalities adapted to intraoperative applications. Simple fluorescence epi-illumination imaging, in particular, appears attractive but may lead to inaccurate observations due to the complex nature of photon-tissue interaction. Of importance therefore are emerging methods that account for the background optical property variation in tissues and can offer accurate, quantitative imaging that eliminates the appearance of false negatives or positives. In parallel, other nonfluorescent optical imaging methods are summarized and overall progress in surgical optical imaging applications is outlined. Key future directions that have the potential to shift the paradigm of surgical health care are also discussed.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
cancer; intraoperative imaging; near-infrared fluorescence; optical imaging; tumor; resection margin; lymph node detection
Language
english
Publication Year
2010
HGF-reported in Year
2010
ISSN (print) / ISBN
1083-3668
e-ISSN
1560-2281
Journal
Journal of Biomedical Optics
Quellenangaben
Volume: 15,
Issue: 6,
Article Number: 066024
Publisher
SPIE
Publishing Place
Bellingham, WA
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-505500-001
PubMed ID
21198198
Erfassungsdatum
2010-12-31