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Evolutionary conservation and cell type specificity of nuclear compartments in the brain.

Trends Neurosci. 45, 3-5 (2021)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
In the cell nucleus, radial genome organization relative to the nuclear lamina exhibits both cell type–specific variability and evolutionarily conserved distribution. A recent study by Ahanger, Delgado et al. explores the in vivo spatial distribution of the genome in the brain and identifies conserved genomic localization across mammalian species that are correlated with gene expression states.
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Publication type Article: Journal article
Document type Letter to the Editor
Keywords Human Cortex ; Lamin B ; Lamina-associated Domain (lad) ; Spatial Genome Organization ; Speckle-associated Domain (spad); Organization; Dynamics
Language english
Publication Year 2021
HGF-reported in Year 2021
ISSN (print) / ISBN 0166-2236
e-ISSN 1878-108X
Quellenangaben Volume: 45, Issue: 1, Pages: 3-5 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Amsterdam [u.a.]
Reviewing status Peer reviewed
Institute(s) Helmholtz Pioneer Campus (HPC)
POF-Topic(s) 30204 - Cell Programming and Repair
30205 - Bioengineering and Digital Health
Research field(s) Pioneer Campus
PSP Element(s) G-510004-001
G-510000-001
Grants Helmholtz Pioneer Campus
HelmholtzGemeinschaft
DFG
Scopus ID 85118261333
PubMed ID 34756461
Erfassungsdatum 2021-12-15