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Schutzmeier, P.* ; Kutzora, S.* ; Mittermeier, I.* ; Becker, J. ; Bergmann, K.C.* ; Bose-O'Reilly, S.* ; Buters, J.T.M. ; Damialis, A. ; Heinrich, J.* ; Kabesch, M.* ; Mertes, H.* ; Nowak, D.* ; Korbely, C.* ; Walser-Reichenbach, S.M.* ; Weinberger, A.* ; Heinze, S.* ; Steckling-Muschack, N.* ; Herr, C.*

Non-pharmacological interventions for pollen-induced allergic symptoms: Systematic literature review.

Pediatr. Allergy Immunol. 33:e13690 (2022)

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BACKGROUND: Allergic diseases pose a health problem worldwide. Pollen are widespread aeroallergens which can cause symptoms like shortness of breath, cough, itchy eyes or rhinitis. Apart from preventive measures and pharmacological treatment, also non-pharmacological interventions have been suggested to reduce symptoms. The objective of this work was to review studies investigating the effectiveness of non-pharmacologic interventions to reduce allergic symptoms. METHODS: PubMed, EMBASE and CENTRAL were systematically reviewed in July 2018 and April 2020. Several authors worked on the screening of titles, abstracts and full texts. One author for each literature search performed the data extraction and the Risk of Bias assessment. Studies were included if they met the inclusion criteria defined by the PECOs. Studies which investigating the effect of non-pharmacologic interventions on patients with allergic rhinitis were included. RESULTS: 29 studies investigating eleven types of non-pharmacologic interventions to avoid and reduce allergic symptoms due to pollen exposure were included in this review. Out of all studies, seven studies addressed nasal rinsing and 22 included acupuncture, air filtering, artisanal tears, individual allergen avoidance advice, various nasal applications, self-hypnosis, rhinophototherapy and wraparound sunglasses. CONCLUSION: Most studies had a high Risk of Bias and small sample sizes. There were only a few high-quality studies that give hints about the effectiveness of non-pharmacological interventions. For future research, more high-quality studies are required to confirm the effectiveness of simple, safe and cost-effective interventions.

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Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

Keywords Allergic Symptoms ; Allergy ; Non-pharmacological Interventions ; Pollen; Randomized Controlled-trial; Applied Cellulose Powder; Double-blind; Nasal Irrigation; Hay-fever; Hypertonic Saline; Rhinitis; Asthma; Children; Acupuncture

ISSN (print) / ISBN 0905-6157

e-ISSN 1399-3038

Journal Pediatric Allergy and Immunology

Quellenangaben Volume: 33, Issue: 1, Article Number: e13690

Publisher Wiley

Publishing Place 111 River St, Hoboken 07030-5774, Nj Usa

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Health Economics and Health Care Management (IGM)
Institute for Allergy Research (IAF)
Institute of Environmental Medicine (IEM)

Grants Bavarian State Ministry of Health and Care