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Aragón-Vela, J.* ; Solis-Urra, P.* ; Ruiz Ojeda, F.J. ; Álvarez-Mercado, A.I.* ; Olivares-Arancibia, J.* ; Plaza-Díaz, J.*

Impact of exercise on gut microbiota in obesity.

Nutrients 13:3999 (2021)
Publ. Version/Full Text DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Physical activity, exercise, or physical fitness are being studied as helpful nonpharmaco-logical therapies to reduce signaling pathways related to inflammation. Studies describing changes in intestinal microbiota have stated that physical activity could increase the microbial variance and enhance the ratio of Firmicutes/Bacteroidetes, and both actions could neutralize the obesity progression and diminish body weight. The aim of this review is to provide an overview of the literature describing the relationship between physical activity profiles and gut microbiota and in obesity and some associated comorbidities. Promoting physical activity could support as a treatment to maintain the gut microbiota composition or to restore the balance toward an improvement of dysbiosis in obesity; however, these mechanisms need to be studied in more detail. The opportunity to control the microbiota by physical activity to improve health results and decrease obesity and related comorbidities is very attractive. Nevertheless, several incompletely answered questions need to be addressed before this strategy can be implemented.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords Children ; Gut Microbiota ; Health ; Humans ; Non-communicable Diseases ; Obesity ; Physical Activity; Farnesoid X Receptor; Chain Fatty-acids; Physical-activity; Weight-loss; Appetite Regulation; Body-composition; Adipose-tissue; Disease; Health; Mechanisms
ISSN (print) / ISBN 2072-6643
e-ISSN 2072-6643
Journal Nutrients
Quellenangaben Volume: 13, Issue: 11, Pages: , Article Number: 3999 Supplement: ,
Publisher MDPI
Publishing Place Basel
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Diabetes and Obesity (IDO)
Grants Agencia Estatal de Investigacion (AEI)
Fundación Ramón Areces
Fundación Alfonso Martín Escudero
University of Granada
National Agency for Research and Development