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Caspase-8: Clipping off RIG-I signaling.
Immunity 34, 283-285 (2011)
Activation of the RIG-I signaling molecule is essential for antiviral immunity but mechanisms downmodulating the response are ill defined. In this issue of Immunity, Rajput et al. (2011) describe caspase-8-mediated RIP1 cleavage as a key step for restricting RIG-I signaling.
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Publication type
Article: Journal article
Document type
Editorial
Keywords
recognition; activation; receptors; nemo
ISSN (print) / ISBN
1074-7613
e-ISSN
1097-4180
Journal
Immunity
Quellenangaben
Volume: 34,
Issue: 3,
Pages: 283-285
Publisher
Cell Press
Publishing Place
Cambridge, Mass.
Reviewing status
Peer reviewed