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Pawlow, X. ; Ott, R. ; Winkler, C. ; Ziegler, A.-G. ; Hummel, S.

A new mathematical approach to improve the original dietary inflammatory index (DII) calculation.

PLoS ONE 16:e0259629 (2021)

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	Open Access Gold

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Accumulating evidence links dietary intake to inflammatory processes involved in non-communicable disease (NCD) development. The dietary inflammatory index (DII) designed by Shivappa et al. has been shown to capture the inflammatory potential of dietary behavior in a large number of epidemiological studies. Thus, the DII may serve as future tool to assess someone's nutritional inflammatory capacities and hence, the individual risks for NCD development later in life. The calculation method of the DII, however, can benefit from alternative mathematical steps, particularly regarding the transformation from standardized daily food consumption to percentile scores. Here, we provide novel approaches, the scaling-formula (SF) and scaling-formula with outlier detection (SFOD) methods, with the aim to optimize the DII calculation method proposed by Shivappa and colleagues. We illustrate on simulated data specific limitations of the original DII calculation and show the benefits of the SF/SFOD by using simulated data and data from the prospective TEENDIAB study cohort, which supports the application of SF/SFOD in future epidemiological and clinical studies.

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Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

Keywords Fatty-acids; Risk; Mortality; Children

ISSN (print) / ISBN 1932-6203

Journal PLoS ONE

Quellenangaben Volume: 16, Issue: 11, Article Number: e0259629

Publisher Public Library of Science (PLoS)

Publishing Place Lawrence, Kan.

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Diabetes Research Type 1 (IDF)

Grants Diabetes Hilfs-und Forschungsfond Deutschland (DHFD)
Kompetenznetz Diabetes mellitus (Competence Network for Diabetes mellitus) - Federal Ministry of Education and Research
H2020 Joint Programming Initiative a Healthy Diet for a Healthy Life (JPI HDHL)