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Open Access Green as soon as Postprint is submitted to ZB.
Retrotransposing a promoter for development.
Nat. Cell Biol. 23, 1221-1223 (2021)
Formerly regarded as 'junk' DNA, transposable elements are now thought to be players in genome evolution. A new study reveals remarkable conservation of a retrotransposon insertion acting as an alternative promoter to drive the expression of a cell cycle regulator isoform in early embryos, potentially controlling the timing of pre-implantation development.
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Publication type
Article: Journal article
Document type
Editorial
Keywords
Mouse; Elements; Enhancer; Line-1; Genes
ISSN (print) / ISBN
1465-7392
e-ISSN
1476-4679
Journal
Nature Cell Biology
Quellenangaben
Volume: 23,
Pages: 1221-1223
Publisher
Nature Publishing Group
Publishing Place
Heidelberger Platz 3, Berlin, 14197, Germany
Reviewing status
Peer reviewed
Institute(s)
Institute of Epigenetics and Stem Cells (IES)
Grants
Deutsche Forschungsgemeinschaft (German Research Foundation)