Retrotransposing a promoter for development.
    
    
        
    
    
        
        Nat. Cell Biol. 23, 1221-1223 (2021)
    
    
 	
    
	
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			Open Access Green as soon as Postprint is submitted to ZB.
		
     
    
      
      
	
	    Formerly regarded as 'junk' DNA, transposable elements are now thought to be players in genome evolution. A new study reveals remarkable conservation of a retrotransposon insertion acting as an alternative promoter to drive the expression of a cell cycle regulator isoform in early embryos, potentially controlling the timing of pre-implantation development.
	
	
	    
	
       
      
	
	    
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        Publication type
        Article: Journal article
    
 
    
        Document type
        Editorial
    
 
    
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        Keywords
        Mouse; Elements; Enhancer; Line-1; Genes
    
 
    
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        Language
        english
    
 
    
        Publication Year
        2021
    
 
    
        Prepublished in Year
        
    
 
    
        HGF-reported in Year
        2021
    
 
    
    
        ISSN (print) / ISBN
        1465-7392
    
 
    
        e-ISSN
        1476-4679
    
 
    
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	    Volume: 23,  
	    Issue: ,  
	    Pages: 1221-1223 
	    Article Number: ,  
	    Supplement: ,  
	
    
 
    
        
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            Publisher
            Nature Publishing Group
        
 
        
            Publishing Place
            Heidelberger Platz 3, Berlin, 14197, Germany
        
 
	
        
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        Reviewing status
        Peer reviewed
    
 
     
    
        POF-Topic(s)
        30204 - Cell Programming and Repair
    
 
    
        Research field(s)
        Stem Cell and Neuroscience
    
 
    
        PSP Element(s)
        G-506200-001
    
 
    
        Grants
        Deutsche Forschungsgemeinschaft (German Research Foundation)
    
 
    
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        Erfassungsdatum
        2021-12-22