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Maya-Manzano, J.M. ; Pusch, G. ; Ebner von Eschenbach, C. ; Bartusel, E. ; Belzner, t. ; Karg, E. ; Bardolatzy, U. ; Scheja, M.* ; Schmidt-Weber, C.B. ; Buters, J.T.M.

Effect of air filtration on house dust mite, cat and dog allergens and particulate matter in homes.

Clin. Transl. Allergy 12:e12137 (2022)

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Background: Indoor allergens (i.e. from mite, cat and dog) are carried by airborne particulate matter. Thus, removal of particles would reduce allergen exposure. This work aims to assess the performance of air filtration on particulate matter and thus allergen removal in 22 bedrooms. Methods: Indoor air was sampled (with and without air filtration) with a cascade impactor and allergens were measured using enzyme-linked immunosorbent assay (ELISA). Particulate matter (including ultrafine particles) was also monitored. Results: The median of allergen reduction was 75.2% for Der f 1 (p < 0.001, n = 20), 65.5% for Der p 1 (p = 0.066, n = 4), 76.6% for Fel d 1 (p < 0.01, n = 21) and 89.3% for Can f 1 (p < 0.01, n = 10). For size fractions, reductions were statistically significant for Der f 1 (all p < 0.001), Can f 1 (PM>10 and PM2.5–10, p < 0.01) and Fel d 1 (PM2.5–10, p < 0.01), but not for Der p 1 (all p > 0.05). PM was reduced in all fractions (p < 0.001). The allergens were found in all particle size fractions, higher mite allergens in the PM>10 and for pet allergens in the PM2.5–10. Conclusions: Air filtration was effective in removing mites, cat and dog allergens and also particulate matter from ambient indoor air, offering a fast and simple solution to mitigate allergen exposome.

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Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

Keywords Air Filtration ; Hepa ; Indoor Allergens ; Particulate Matter ; Ufp

e-ISSN 2045-7022

Journal Clinical and Translational Allergy

Quellenangaben Volume: 12, Issue: 4, Article Number: e12137

Publisher BioMed Central

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute for Allergy Research (IAF)

Grants Philips