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Heeman, W.* ; Vonk, J.* ; Ntziachristos, V. ; Pogue, B.W.* ; Dierckx, R.A.J.O.* ; Kruijff, S.* ; van Dam, G.M.*

A guideline for clinicians performing clinical studies with fluorescence imaging.

J. Nucl. Med. 63, 640-645 (2022)
Publ. Version/Full Text DOI PMC
Open Access Hybrid
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Fluorescence imaging is an emerging imaging technique that has shown many benefits for clinical care. Currently, the field is in rapid clinical translation, and an unprecedented number of clinical trials are performed. Clinicians are inundated with numerous opportunities and combinations of different imaging modalities. To streamline this process, a multidisciplinary approach is needed with drug discovery, software and systems engineering, and translational medicine. Here, we discuss the main constituents of a uniform fluorescence imaging protocol to match the clinical need and ensure consistent study designs and reliable data collection in clinical trials. In an era in which the potential of fluorescence imaging has become evident, consistent conduct of studies, data analysis, and data interpretation is essential for implementation into the standard of care.
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Publication type Article: Journal article
Document type Review
Keywords Clinical Translation ; Fluorescence Imaging ; Molecular Imaging ; Optical ; Optical Imaging ; Research Methods
Language english
Publication Year 2022
HGF-reported in Year 2022
ISSN (print) / ISBN 0161-5505
e-ISSN 1535-5667
Journal Journal of Nuclear Medicine
Quellenangaben Volume: 63, Issue: 5, Pages: 640-645 Article Number: , Supplement: ,
Publisher Society of Nuclear Medicine and Molecular Imaging
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)
POF-Topic(s) 30205 - Bioengineering and Digital Health
Research field(s) Enabling and Novel Technologies
PSP Element(s) G-505500-001
DOI 10.2967/jnumed.121.262975
WOS ID WOS:000792496500002
Scopus ID 85129521894
PubMed ID 35145017
Erfassungsdatum 2022-05-16
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