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Heeman, W.* ; Vonk, J.* ; Ntziachristos, V. ; Pogue, B.W.* ; Dierckx, R.A.J.O.* ; Kruijff, S.* ; van Dam, G.M.*

A guideline for clinicians performing clinical studies with fluorescence imaging.

J. Nucl. Med. 63, 640-645 (2022)
Publ. Version/Full Text DOI PMC
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Fluorescence imaging is an emerging imaging technique that has shown many benefits for clinical care. Currently, the field is in rapid clinical translation, and an unprecedented number of clinical trials are performed. Clinicians are inundated with numerous opportunities and combinations of different imaging modalities. To streamline this process, a multidisciplinary approach is needed with drug discovery, software and systems engineering, and translational medicine. Here, we discuss the main constituents of a uniform fluorescence imaging protocol to match the clinical need and ensure consistent study designs and reliable data collection in clinical trials. In an era in which the potential of fluorescence imaging has become evident, consistent conduct of studies, data analysis, and data interpretation is essential for implementation into the standard of care.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords Clinical Translation ; Fluorescence Imaging ; Molecular Imaging ; Optical ; Optical Imaging ; Research Methods
ISSN (print) / ISBN 0161-5505
e-ISSN 1535-5667
Quellenangaben Volume: 63, Issue: 5, Pages: 640-645 Article Number: , Supplement: ,
Publisher Society of Nuclear Medicine and Molecular Imaging
Non-patent literature Publications
Reviewing status Peer reviewed