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Schnabel, J.A.* ; Tanner, C.* ; Smith, A.D.C.* ; Leach, M.O.* ; Hayes, C.* ; Degenhard, A.* ; Hose, R.* ; Hill, D.L.G.* ; Hawkes, D.J.*

Validation of non-rigid registration using finite element methods.

In: (Biennial International Conference on Information Processing in Medical Imaging). Berlin [u.a.]: Springer, 2001. 344-357 (Lect. Notes Comput. Sc. ; 2082)
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Open Access Green as soon as Postprint is submitted to ZB.
We present a novel validation method for non-rigid registration using a simulation of deformations based on biomechanical modelling of tissue properties. This method is tested on a previously developed non-rigid registration method for dynamic contrast enhanced Magnetic Resonance (MR) mammography image pairs [1]. We have constructed finite element breast models and applied a range of displacements to them, with an emphasis on generating physically plausible deformations which may occur during normal patient scanning procedures. From the finite element method (FEM) solutions, we have generated a set of deformed contrast enhanced images against which we have registered the original dynamic image pairs. The registration results have been successfully validated at all breast tissue locations by comparing the recovered displacements with the biomechanical displacements. The validation method presented in this paper is an important tool to provide biomechanical gold standard deformations for registration error quantification, which may also form the basis to improve and compare different non-rigid registration techniques for a diversity of medical applications.
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Publication type Article: Conference contribution
Corresponding Author
ISSN (print) / ISBN 0302-9743
e-ISSN 1611-3349
Conference Title Biennial International Conference on Information Processing in Medical Imaging
Quellenangaben Volume: 2082, Issue: , Pages: 344-357 Article Number: , Supplement: ,
Publisher Springer
Publishing Place Berlin [u.a.]
Non-patent literature Publications
Institute(s) Institute for Machine Learning in Biomed Imaging (IML)