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Babalola, K.O.* ; Patenaude, B.* ; Aljabar, P.* ; Schnabel, J.A.* ; Kennedy, D.* ; Crum, W.R.* ; Smith, S.* ; Cootes, T.F.* ; Jenkinson, M.* ; Rueckert, D.*

Comparison and evaluation of segmentation techniques for subcortical structures in brain MRI.

In: (International Conference on Medical Image Computing and Computer-Assisted Intervention). Berlin [u.a.]: Springer, 2008. 409-416 (Lect. Notes Comput. Sc. ; 5241 LNCS)
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Open Access Green as soon as Postprint is submitted to ZB.
The automation of segmentation of medical images is an active research area. However, there has been criticism of the standard of evaluation of methods. We have comprehensively evaluated four novel methods of automatically segmenting subcortical structures using volumetric, spatial overlap and distance-based measures. Two of the methods are atlas-based - classifier fusion and labelling (CFL) and expectation-maximisation segmentation using a dynamic brain atlas (EMS), and two model-based - profile active appearance models (PAM) and Bayesian appearance models (BAM). Each method was applied to the segmentation of 18 subcortical structures in 270 subjects from a diverse pool varying in age, disease, sex and image acquisition parameters. Our results showed that all four methods perform on par with recently published methods. CFL performed significantly better than the other three methods according to all three classes of metrics. © 2008 Springer-Verlag Berlin Heidelberg.
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Publication type Article: Conference contribution
Corresponding Author
ISSN (print) / ISBN 0302-9743
e-ISSN 1611-3349
Conference Title International Conference on Medical Image Computing and Computer-Assisted Intervention
Quellenangaben Volume: 5241 LNCS, Issue: PART 1, Pages: 409-416 Article Number: , Supplement: ,
Publisher Springer
Publishing Place Berlin [u.a.]
Non-patent literature Publications
Institute(s) Institute for Machine Learning in Biomed Imaging (IML)