Schnabel, J.A.* ; Lemieux, L.* ; Wieshmann, U.C.* ; Arridge, S.R.*
    
    
        
Measurement of hippocampal volume changes in serial MRI scans.
    
    
        
    
    
        
        Proc. SPIE 3661, 1367-1376 (1999)
    
    
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	    We present a new method for the detection and measurement of volume changes in human hippocampi in serial Magnetic Resonance Imaging (MRI). The method follows a two-stage approach: (1) precise co-registration and intensity matching of the initial (baseline) and follow-up scan, and (2) refinement and segmentation propagation of the hippocampi outlines drawn in the baseline scan by an expert observer to the matched scan (co-registered and intensity matched follow-up scan of the time series). The first step is performed using MRreg, a rigid registration tool based on cross-correlation and intensity matching, and the second step makes use of the concept of active contour models for tracking the hippocampi outlines in the time series.
	
	
	    
	
       
      
	
	    
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        Publication type
        Article: Journal article
    
 
    
        Document type
        Scientific Article
    
 
    
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        Language
        english
    
 
    
        Publication Year
        1999
    
 
    
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        HGF-reported in Year
        1999
    
 
    
    
        ISSN (print) / ISBN
        0277-786X
    
 
    
        e-ISSN
        1996-756X
    
 
    
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	    Volume: 3661,  
	    Issue: II,  
	    Pages: 1367-1376 
	    Article Number: ,  
	    Supplement: ,  
	
    
 
    
        
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            SPIE
        
 
        
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        Peer reviewed
    
 
    
        Institute(s)
        Institute for Machine Learning in Biomed Imaging (IML)
    
 
    
        POF-Topic(s)
        30205 - Bioengineering and Digital Health
    
 
    
        Research field(s)
        Enabling and Novel Technologies
    
 
    
        PSP Element(s)
        G-507100-001
    
 
    
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        Erfassungsdatum
        2022-09-05