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Schnabel, J.A.* ; Lemieux, L.* ; Wieshmann, U.C.* ; Arridge, S.R.*

Measurement of hippocampal volume changes in serial MRI scans.

Proc. SPIE 3661, 1367-1376 (1999)
Open Access Green as soon as Postprint is submitted to ZB.
We present a new method for the detection and measurement of volume changes in human hippocampi in serial Magnetic Resonance Imaging (MRI). The method follows a two-stage approach: (1) precise co-registration and intensity matching of the initial (baseline) and follow-up scan, and (2) refinement and segmentation propagation of the hippocampi outlines drawn in the baseline scan by an expert observer to the matched scan (co-registered and intensity matched follow-up scan of the time series). The first step is performed using MRreg, a rigid registration tool based on cross-correlation and intensity matching, and the second step makes use of the concept of active contour models for tracking the hippocampi outlines in the time series.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Quellenangaben Volume: 3661, Issue: II, Pages: 1367-1376 Article Number: , Supplement: ,
Publisher SPIE
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute for Machine Learning in Biomed Imaging (IML)