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Nonlinear smoothing for reduction of systematic and random errors in diffusion tensor imaging.
J. Magn. Reson. Imaging 11, 702-710 (2000)
Calculation and sorting of the eigenvectors of diffusion using diffusion tensor imaging has previously been shown to be sensitive to noise levels in the acquired data. This sensitivity manifests as random and systematic errors in the diffusion eigenvalues and derived parameters such as indices of anisotropy. An optimized application of nonlinear smoothing techniques to diffusion data prior to calculation of the diffusion tensor is shown to reduce both random and systematic errors, while causing little blurring of anatomical structures. Conversely, filtering applied to calculated images of fractional anisotropy is shown to fail in reducing systematic errors and in recovering anatomical detail. Using both real and simulated brain data sets, it is demonstrated that this approach has the potential to allow acquisition of data that would otherwise be too noisy to be of use. (C) 2000 Wiley-Liss, Inc.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Diffusion Tensor Imaging ; Noise Reduction ; Signal-to- Noise Ratio ; Systematic Errors
Language
english
Publication Year
2000
HGF-reported in Year
2000
ISSN (print) / ISBN
1053-1807
e-ISSN
1522-2586
Quellenangaben
Volume: 11,
Issue: 6,
Pages: 702-710
Publisher
Wiley
Reviewing status
Peer reviewed
Institute(s)
Institute for Machine Learning in Biomed Imaging (IML)
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-507100-001
Scopus ID
0034117676
Erfassungsdatum
2022-09-05