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DIMA 3.0: Domain Interaction Map.
Nucleic Acids Res. 39, 1, D724-D729 (2011)
Domain Interaction MAp (DIMA, available at http://webclu.bio.wzw.tum.de/dima) is a database of predicted and known interactions between protein domains. It integrates 5807 structurally known interactions imported from the iPfam and 3did databases and 46,900 domain interactions predicted by four computational methods: domain phylogenetic profiling, domain pair exclusion algorithm correlated mutations and domain interaction prediction in a discriminative way. Additionally predictions are filtered to exclude those domain pairs that are reported as non-interacting by the Negatome database. The DIMA Web site allows to calculate domain interaction networks either for a domain of interest or for entire organisms, and to explore them interactively using the Flash-based Cytoscape Web software.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
PROTEIN-PROTEIN INTERACTIONS; MULTIPLE SEQUENCE ALIGNMENTS; CORRELATED MUTATIONS; COMPREHENSIVE DATABASE; FAMILIES; WEB; ANNOTATIONS; INTERFACES; NETWORK; PFAM
ISSN (print) / ISBN
0305-1048
e-ISSN
1362-4962
Journal
Nucleic Acids Research
Quellenangaben
Volume: 39,
Issue: SUPPL. 1,
Pages: D724-D729,
Supplement: 1
Publisher
Oxford University Press
Non-patent literature
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Reviewing status
Peer reviewed