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1H, 13C, 15N and 31P chemical shift assignments of a human Xist RNA A-repeat tetraloop hairpin essential for X-chromosome inactivation.

Biomol. NMR Assign. 6, 75-77 (2012)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Initiation of X-chromosome inactivation in female mammals depends on the non-coding RNA Xist. We have solved the NMR structure of a 14-nucleotide hairpin with a novel AUCG tetraloop fold from a Xist A-repeat that is essential for silencing. The (1)H, (13)C, (15)N and (31)P chemical shift assignments are reported.
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Publication type Article: Journal article
Document type Scientific Article
Keywords NMR assignment; non-coding RNA; RNA hairpin; RNA tetraloop; xist RNA a-repeats; X-inactivation; RESONANCES; COUPLINGS
Language english
Publication Year 2012
Prepublished in Year 2011
HGF-reported in Year 2011
ISSN (print) / ISBN 1874-2718
e-ISSN 1874-270X
Quellenangaben Volume: 6, Issue: 1, Pages: 75-77 Article Number: , Supplement: ,
Publisher Springer
Publishing Place Dordrecht, Netherlands
Reviewing status Peer reviewed
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Enabling and Novel Technologies
PSP Element(s) G-503000-001
PubMed ID 21779925
Scopus ID 84858297991
Erfassungsdatum 2011-11-08