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1H, 13C, 15N and 31P chemical shift assignments of a human Xist RNA A-repeat tetraloop hairpin essential for X-chromosome inactivation.
Biomol. NMR Assign. 6, 75-77 (2012)
Initiation of X-chromosome inactivation in female mammals depends on the non-coding RNA Xist. We have solved the NMR structure of a 14-nucleotide hairpin with a novel AUCG tetraloop fold from a Xist A-repeat that is essential for silencing. The (1)H, (13)C, (15)N and (31)P chemical shift assignments are reported.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
NMR assignment; non-coding RNA; RNA hairpin; RNA tetraloop; xist RNA a-repeats; X-inactivation; RESONANCES; COUPLINGS
Language
english
Publication Year
2012
Prepublished in Year
2011
HGF-reported in Year
2011
ISSN (print) / ISBN
1874-2718
e-ISSN
1874-270X
Journal
Biomolecular NMR Assignments
Quellenangaben
Volume: 6,
Issue: 1,
Pages: 75-77
Publisher
Springer
Publishing Place
Dordrecht, Netherlands
Reviewing status
Peer reviewed
Institute(s)
Institute of Structural Biology (STB)
POF-Topic(s)
30203 - Molecular Targets and Therapies
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-503000-001
PubMed ID
21779925
Scopus ID
84858297991
Erfassungsdatum
2011-11-08