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Licenced for HMGU: Publ. Version/Full Text online available 10/2025
as soon as is submitted to ZB.
Improving biomedical research by automated behaviour monitoring in the animal home cage - action needed for networking.
Lab. Anim. 57, 79-83 (2023)
Postprint
DOI
PMC
The key goal in biomedical research is a better understanding of disease aetiologies, which ideally results in strategies and recommendations for the prevention of diseases before they arise, and in the development of effective therapies. However, many concerns have been expressed about the reproducibility and the translational validity of preclinical research in animal models to inform clinical trials in humans. It has been proposed that improving internal, external and construct validity of animal studies will lead to improved translatability. Automated behaviour monitoring in the animal's home cage, which allows for longitudinal assessment of individual trajectories over sufficiently long intervals for (chronic) drug treatment or phenotype progression, is a promising solution to these problems.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Home Cage Monitoring ; Cost Action ; Networking ; Three Rs
ISSN (print) / ISBN
0023-6772
e-ISSN
1758-1117
Journal
Laboratory animals
Quellenangaben
Volume: 57,
Issue: 1,
Pages: 79-83
Publisher
Sage
Publishing Place
London
Non-patent literature
Publications
Institute(s)
Institute of Developmental Genetics (IDG)
Grants
Jane and Aatos Erkko Foundation