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Schroeder, T.

Long-term single-cell imaging of mammalian stem cells.

Nat. Methods 8, Suppl. S, S30-S35 (2011)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Continuous long-term single-cell observation provides insight into the molecular control of cell fate. This is particularly important for rare and heterogeneous populations of cells, such as mammalian stem cells. The current lack of usable off-the-shelf hardware and software for such experiments makes their implementation technically challenging. Here I discuss the need for continuous single-cell quantification to understand molecular cell fate control as well as organizational and technical solutions for long-term imaging and tracking of stem cells.
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Publication type Article: Journal article
Document type Scientific Article
Keywords mouse cerebral-cortex; hematopoietic stem; in-vitro; progenitor cells; self-renewal; postnatal astroglia; systems biology; lineage choice; fate; generation
Language english
Publication Year 2011
HGF-reported in Year 2011
ISSN (print) / ISBN 1548-7091
e-ISSN 1548-7105
Journal Nature Methods
Quellenangaben Volume: 8, Issue: 4, Pages: S30-S35, Article Number: , Supplement: Suppl. S
Publisher Nature Publishing Group
Publishing Place New York, NY
Reviewing status Peer reviewed
Institute(s) Research Unit Stem Cell Dynamics (SCD)
POF-Topic(s) 30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
Research field(s) Stem Cell and Neuroscience
PSP Element(s) G-501200-001
PubMed ID 21451514
DOI 10.1038/NMETH.1577
Scopus ID 79953280811
Erfassungsdatum 2011-11-09
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