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Radiation dose rate effects: What is new and what is needed?
Radiat. Environ. Biophys. 61, 507-543 (2022)
Despite decades of research to understand the biological effects of ionising radiation, there is still much uncertainty over the role of dose rate. Motivated by a virtual workshop on the "Effects of spatial and temporal variation in dose delivery" organised in November 2020 by the Multidisciplinary Low Dose Initiative (MELODI), here, we review studies to date exploring dose rate effects, highlighting significant findings, recent advances and to provide perspective and recommendations for requirements and direction of future work. A comprehensive range of studies is considered, including molecular, cellular, animal, and human studies, with a focus on low linear-energy-transfer radiation exposure. Limits and advantages of each type of study are discussed, and a focus is made on future research needs.
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Publication type
Article: Journal article
Document type
Review
Keywords
Dose Rate ; Epidemiology ; Ionising Radiation ; Low-let ; Radiobiology ; Recommendations
ISSN (print) / ISBN
0301-634X
e-ISSN
1432-2099
Quellenangaben
Volume: 61,
Issue: 4,
Pages: 507-543
Publisher
Springer
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Radiation Medicine (IRM)