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Korbmacher-Boettcher, D.* ; Bamberg, F.* ; Peters, A. ; Linkohr, B. ; Ladwig, K.-H. ; Schwettmann, L. ; Weckbach, S.* ; Schlett, C.L.* ; Rospleszcz, S.

Long-term psychosocial consequences of whole-body magnetic resonance imaging and reporting of incidental findings in a population-based cohort study.

Diagnostics 12:2356 (2022)
Publ. Version/Full Text DOI PMC
Open Access Gold
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Management of radiological incidental findings (IF) is of rising importance; however, psychosocial implications of IF reporting remain unclear. We compared long-term psychosocial effects between individuals who underwent whole-body magnetic resonance imaging (MRI) with and without reported IF, and individuals who did not undergo imaging. We used a longitudinal population-based cohort from Western Europe. Longitudinal analysis included three examinations (exam 1, 6 years prior to MRI; exam 2, MRI; exam 3, 4 years after MRI). Psychosocial outcomes included PHQ-9 (Patient Health Questionnaire), DEEX (Depression and Exhaustion Scale), PSS-10 (Perceived Stress Scale) and a Somatization Scale. Univariate analyses and adjusted linear mixed models were calculated. Among 855 included individuals, 25% (n = 212) underwent MRI and 6% (n = 50) had at least one reported IF. Compared to MRI participants, non-participants had a higher psychosocial burden indicated by PHQ-9 in exam 1 (3.3 ± 3.3 vs. 2.5 ± 2.3) and DEEX (8.6 ± 4.7 vs. 7.7 ± 4.4), Somatization Scale (5.9 ± 4.3 vs. 4.8 ± 3.8) and PSS-10 (14.7 ± 5.7 vs. 13.7 ± 5.3, all p < 0.05) in exam 3. MRI participation without IF reporting was significantly associated with lower values of DEEX, PHQ-9 and Somatization Scale. There were no significant differences at the three timepoints between MRI participants with and without IF. In conclusion, individuals who voluntarily participated in whole-body MRI had less psychosocial burden and imaging and IF reporting were not associated with adverse long-term psychosocial consequences. However, due to the study design we cannot conclude that the MRI exam itself represented a beneficial intervention causing improvement in mental health scores.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Mental Health ; Incidental Findings ; Magnetic Resonance Imaging ; Whole Body Imaging ; Longitudinal Study
ISSN (print) / ISBN 2075-4418
e-ISSN 2075-4418
Journal Diagnostics
Quellenangaben Volume: 12, Issue: 10, Pages: , Article Number: 2356 Supplement: ,
Publisher MDPI
Non-patent literature Publications
Reviewing status Peer reviewed