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Göllner, S. ; Mishra, K. ; Stiel, A.-C.

Schallschalter: Photoschaltbare Reporter und Sensoren in der Optoakustik.

BioSpektrum 28, 711-715 (2022)
Publ. Version/Full Text DOI
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Optoacoustic imaging offers a unique combination of observation volume and achievable resolution in vivo. However, the use of transgene labeling agents has been impractical because their signal is low compared to the background of the tissue. Thus, detection was limited to large numbers of cells. We tackle this problem by using switchable agents — switching creates a signal modulation which allows to separate the labeled cells from the constant background — making it virtually invisible.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0947-0867
e-ISSN 1868-6249
Journal BioSpektrum
Quellenangaben Volume: 28, Issue: 7, Pages: 711-715 Article Number: , Supplement: ,
Publisher Springer
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)
Grants Deutsche Forschungsgemeinschaft
Innovationsprogramms Horizon 2020 der Europäischen Union unter der Finanzhilfevereinbarung
Europäischen Forschungsrat
Arbeitsgruppe Cell Engineering werden gefördert durch die Deutsche Forschungsgemeinschaft