Duarte, A.I.* ; Sadowska-Bartosz, I.* ; Karkucinska-Wieckowska, A.* ; Lebiedzinska-Arciszewska, M.* ; Palmeira, C.M.* ; Rolo, A.P.* ; Kabiri, Y.* ; Zavan, B.* ; Pinton, P.* ; Borges, F.* ; Zischka, H. ; Jones, J.G.* ; Bartosz, G.* ; Oliveira, P.J.* ; Wieckowski, M.R.*
     
    
        
A metabolic and mitochondrial angle on aging.
    
    
        
    
    
        
        In: From Fundamental Biology to Societal Impact. Impact Journals LLC, 2023. 175-256 (Aging)
    
    
 	
    
	
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	    The increasingly aged human population (mainly in developed countries) represents a significant scientific achievement and privilege associated with medical, social, and economic progress. However, it also poses several challenges to national health and social care systems. The uncoupling of biological evolution with the vast and fast technical progress achieved by humanity has minimized the role of natural selection and rendered aging almost an undesirable physiological event that most people desire to delay as much as possible. All this has been challenging modern gerontology to focus on potential strategies to extend the lifespan, but primarily to mitigate the negative thoughts often associated with aging and aged individuals.
	
	
	    
	
       
      
	
	    
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        Publication type
        Article: Edited volume or book chapter
    
 
    
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        Keywords
        Aging ; Lifespan ; Metabolism ; Mitochondria ; Natural Selection ; Reactive Oxygen Species
    
 
    
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        Language
        english
    
 
    
        Publication Year
        2023
    
 
    
        Prepublished in Year
        2022
    
 
    
        HGF-reported in Year
        2022
    
 
    
    
        ISSN (print) / ISBN
        1945-4589
    
 
    
        e-ISSN
        1945-4589
    
 
    
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        Book Volume Title
        From Fundamental Biology to Societal Impact
    
 
    
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	    Volume: ,  
	    Issue: ,  
	    Pages: 175-256 
	    Article Number: ,  
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            Impact Journals LLC
        
 
        
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        Reviewing status
        Peer reviewed
    
 
     
    
        POF-Topic(s)
        30203 - Molecular Targets and Therapies
    
 
    
        Research field(s)
        Enabling and Novel Technologies
    
 
    
        PSP Element(s)
        G-505200-003
    
 
    
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        Erfassungsdatum
        2022-12-07