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Jastroch, M.* ; Keipert, S.* ; Tschöp, M.H.

Protection from alcohol intoxication: Must be FGF21 to enter.

Cell Metab. 35, 377-379 (2023)
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Fibroblast growth factor 21 (FGF21) is generally known as a stress-induced metabolic regulator with enormous therapeutic potential to treat metabolic diseases, but a more specific role of FGF21 concerns physiological handling of alcohol in mammals. In this issue of Cell Metabolism, Choi et al. demonstrate that FGF21 mediates the recovery from alcohol intoxication by directly activating noradrenergic neurons in mice, thus advancing our knowledge on FGF21 biology and further diversifying its therapeutic potential.
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Publication type Article: Journal article
Document type Letter to the Editor
Corresponding Author
Keywords Activation; Ethanol
ISSN (print) / ISBN 1550-4131
e-ISSN 1932-7420
Journal Cell Metabolism
Quellenangaben Volume: 35, Issue: 3, Pages: 377-379 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place 50 Hampshire St, Floor 5, Cambridge, Ma 02139 Usa
Non-patent literature Publications
Reviewing status Peer reviewed
Grants Formas
Swedish Research Council
Novo Nordisk Research Foundation