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Protection from alcohol intoxication: Must be FGF21 to enter.
Cell Metab. 35, 377-379 (2023)
Fibroblast growth factor 21 (FGF21) is generally known as a stress-induced metabolic regulator with enormous therapeutic potential to treat metabolic diseases, but a more specific role of FGF21 concerns physiological handling of alcohol in mammals. In this issue of Cell Metabolism, Choi et al. demonstrate that FGF21 mediates the recovery from alcohol intoxication by directly activating noradrenergic neurons in mice, thus advancing our knowledge on FGF21 biology and further diversifying its therapeutic potential.
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Publication type
Article: Journal article
Document type
Letter to the Editor
Keywords
Activation; Ethanol
ISSN (print) / ISBN
1550-4131
e-ISSN
1932-7420
Journal
Cell Metabolism
Quellenangaben
Volume: 35,
Issue: 3,
Pages: 377-379
Publisher
Elsevier
Publishing Place
50 Hampshire St, Floor 5, Cambridge, Ma 02139 Usa
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Obesity (IDO)
Grants
Formas
Swedish Research Council
Novo Nordisk Research Foundation
Swedish Research Council
Novo Nordisk Research Foundation