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Open Access Green as soon as Postprint is submitted to ZB.
Nonmetabolic role for CKB in ferroptosis.
Nat. Cell Biol. 25, 633-634 (2023)
The selenoprotein glutathione peroxidase 4 (GPX4) is the guardian of ferroptosis, a form of cell death earmarked by unrestrained lipid peroxidation. A new study shows that the metabolic enzyme creatinine kinase B (CKB) phosphorylates GPX4, which may influence the susceptibility of cancer cells to ferroptosis.
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Publication type
Article: Journal article
Document type
Letter to the Editor
Keywords
Hydroperoxide Glutathione-peroxidase; Protein; Phgpx; Form
ISSN (print) / ISBN
1465-7392
e-ISSN
1476-4679
Journal
Nature Cell Biology
Quellenangaben
Volume: 25,
Issue: 5,
Pages: 633-634
Publisher
Nature Publishing Group
Publishing Place
Heidelberger Platz 3, Berlin, 14197, Germany
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Metabolism and Cell Death (MCD)