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Shortwave infrared fluorescence imaging of peripheral organs in awake and freely moving mice.

Front. Neurosci. 17:1135494 (2023)
Publ. Version/Full Text DOI PMC
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Extracting biological information from awake and unrestrained mice is imperative to in vivo basic and pre-clinical research. Accordingly, imaging methods which preclude invasiveness, anesthesia, and/or physical restraint enable more physiologically relevant biological data extraction by eliminating these extrinsic confounders. In this article, we discuss the recent development of shortwave infrared (SWIR) fluorescent imaging to visualize peripheral organs in freely-behaving mice, as well as propose potential applications of this imaging modality in the neurosciences.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Awake Imaging ; Fluorescence ; Fluorescent Dyes ; In Vivo Imaging ; Near Infrared (nir)-ii ; Optical Imaging ; Organic Fluorophores ; Polymethine Dyes; Biomedical-research; Restraint Stress; Ii Fluorescence; Brain; Anesthesia; Window
ISSN (print) / ISBN 1662-453X
Quellenangaben Volume: 17, Issue: , Pages: , Article Number: 1135494 Supplement: ,
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Institute(s) Helmholtz Pioneer Campus (HPC)
Grants CZI Deep Tissue Imaging
Helmholtz Pioneer Campus
Emmy-Noether-Program of DFG
Alfred P. Sloan Foundation
Foote Family (EC)
NIH
NSF