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Open Access Green as soon as Postprint is submitted to ZB.
Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo.
J. Nat. Med. 17, 1680-1684 (2011)
Advancing understanding of human coronary artery disease requires new methods that can be used in patients for studying atherosclerotic plaque microstructure in relation to the molecular mechanisms that underlie its initiation, progression and clinical complications, including myocardial infarction and sudden cardiac death. Here we report a dual-modality intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo using a combination of optical frequency domain imaging (OFDI) and near-infrared fluorescence (NIRF) imaging. By providing simultaneous molecular information in the context of the surrounding tissue microstructure, this new catheter could provide new opportunities for investigating coronary atherosclerosis and stent healing and for identifying high-risk biological and structural coronary arterial plaques in vivo.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
no keywords
ISSN (print) / ISBN
1340-3443
e-ISSN
1861-0293
Journal
Journal of natural medicines
Quellenangaben
Volume: 17,
Issue: 12,
Pages: 1680-1684
Publisher
Springer
Publishing Place
Tokyo [u.a.]
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)