PuSH - Publication Server of Helmholtz Zentrum München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Staab-Weijnitz, C.A. ; Onursal, C. ; Nambiar, D.* ; Vanacore, R.*

Assessment of collagen in translational models of lung research.

Adv. Exp. Med. Biol. 1413, 213-244 (2023)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
The extracellular matrix (ECM) plays an important role in lung health and disease. Collagen is the main component of the lung ECM, widely used for the establishment of in vitro and organotypic models of lung disease, and as scaffold material of general interest for the field of lung bioengineering. Collagen also is the main readout for fibrotic lung disease, where collagen composition and molecular properties are drastically changed and ultimately result in dysfunctional "scarred" tissue. Because of the central role of collagen in lung disease, quantification, determination of molecular properties, and three-dimensional visualization of collagen is important for both development and characterization of translational models of lung research. In this chapter, we provide a comprehensive overview on the various methodologies currently available for quantification and characterization of collagen including their detection principles, advantages, and disadvantages.
Impact Factor
Scopus SNIP
Altmetric
0.000
0.000
Tags
Annotations
Special Publikation
Hide on homepage

Edit extra information
Edit own tags
Private
Edit own annotation
Private
Hide on publication lists
on hompage
Mark as special
publikation
Publication type Article: Journal article
Document type Scientific Article
Keywords Collagen Architecture ; Collagen Crosslinking ; Collagen Post-translational Modifications ; Hydroxyproline ; Mass Spectrometry ; Matrisome ; Proteomics; Basement-membrane Collagen; Rat Tail Tendon; Extracellular-matrix; Electron-microscopy; Cross-links; I Collagen; Peptide Identification; Pulmonary-fibrosis; Cell; Fluorescence
Language english
Publication Year 2023
HGF-reported in Year 2023
ISSN (print) / ISBN 0065-2598
Journal Advances in Experimental Medicine and Biology
Quellenangaben Volume: 1413, Issue: , Pages: 213-244 Article Number: , Supplement: ,
Publisher Springer
Publishing Place New York
Reviewing status Peer reviewed
Institute(s) Institute of Lung Health and Immunity (LHI)
POF-Topic(s) 80000 - German Center for Lung Research
30202 - Environmental Health
Research field(s) Lung Research
PSP Element(s) G-501800-817
G-501600-001
Grants
Federal Institute for Risk Assessment (Bundesinstitut fur Risikobewertung, BfR)
Deutsche Forschungsgemeinschaft (DFG)
German Center for Lung Research (DZL)
Helmholtz Association
DOI 10.1007/978-3-031-26625-6_11
WOS ID 001167144000013
Scopus ID 85159770686
PubMed ID 37195533
Erfassungsdatum 2023-10-06
[➜Report correction]