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Verhaegen, F.* ; Butterworth, K.T.* ; Chalmers, A.J.* ; Coppes, R.P.* ; De Ruysscher, D.* ; Dobiasch, S. ; Fenwick, J.D.* ; Granton, P.V.* ; Heijmans, S.H.J.* ; Hill, M.A.* ; Koumenis, C.* ; Lauber, K.* ; Marples, B.* ; Parodi, K.* ; Persoon, L.C.G.G.* ; Staut, N.* ; Subiel, A.* ; Vaes, R.D.W.* ; van Hoof, S.* ; Verginadis, I.L.* ; Wilkens, J.J.* ; Williams, K.J.* ; Wilson, G.D.* ; Dubois, L.J.*

Roadmap for precision preclinical x-ray radiation studies.

Phys. Med. Biol. 68:06RM01 (2023)
DOI PMC
Creative Commons Lizenzvertrag
Open Access Green as soon as Postprint is submitted to ZB.
This Roadmap paper covers the field of precision preclinical x-ray radiation studies in animal models. It is mostly focused on models for cancer and normal tissue response to radiation, but also discusses other disease models. The recent technological evolution in imaging, irradiation, dosimetry and monitoring that have empowered these kinds of studies is discussed, and many developments in the near future are outlined. Finally, clinical translation and reverse translation are discussed.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords Cancer Models ; Dosimetry ; Imaging ; Irradiation ; Precision ; Preclinical ; Translation; Tumor Xenografts; Cardiac Injury; Mouse Model; Radiotherapy; Therapy; Disease; Cancer; Brain; Water; Mice
ISSN (print) / ISBN 0031-9155
e-ISSN 1361-6560
Journal Physics in Medicine and Biology
Quellenangaben Volume: 68, Issue: 6, Pages: , Article Number: 06RM01 Supplement: ,
Publisher Institute of Physics Publishing (IOP)
Publishing Place Bristol
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Radiation Medicine (IRM)