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Verhaegen, F.* ; Butterworth, K.T.* ; Chalmers, A.J.* ; Coppes, R.P.* ; De Ruysscher, D.* ; Dobiasch, S. ; Fenwick, J.D.* ; Granton, P.V.* ; Heijmans, S.H.J.* ; Hill, M.A.* ; Koumenis, C.* ; Lauber, K.* ; Marples, B.* ; Parodi, K.* ; Persoon, L.C.G.G.* ; Staut, N.* ; Subiel, A.* ; Vaes, R.D.W.* ; van Hoof, S.* ; Verginadis, I.L.* ; Wilkens, J.J.* ; Williams, K.J.* ; Wilson, G.D.* ; Dubois, L.J.*

Roadmap for precision preclinical x-ray radiation studies.

Phys. Med. Biol. 68:06RM01 (2023)
Postprint DOI PMC
Open Access Hybrid
Creative Commons Lizenzvertrag
This Roadmap paper covers the field of precision preclinical x-ray radiation studies in animal models. It is mostly focused on models for cancer and normal tissue response to radiation, but also discusses other disease models. The recent technological evolution in imaging, irradiation, dosimetry and monitoring that have empowered these kinds of studies is discussed, and many developments in the near future are outlined. Finally, clinical translation and reverse translation are discussed.
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Publication type Article: Journal article
Document type Review
Keywords Cancer Models ; Dosimetry ; Imaging ; Irradiation ; Precision ; Preclinical ; Translation; Tumor Xenografts; Cardiac Injury; Mouse Model; Radiotherapy; Therapy; Disease; Cancer; Brain; Water; Mice
Language english
Publication Year 2023
HGF-reported in Year 2023
ISSN (print) / ISBN 0031-9155
e-ISSN 1361-6560
Journal Physics in Medicine and Biology
Quellenangaben Volume: 68, Issue: 6, Pages: , Article Number: 06RM01 Supplement: ,
Publisher Institute of Physics Publishing (IOP)
Publishing Place Bristol
Reviewing status Peer reviewed
Institute(s) Institute of Radiation Medicine (IRM)
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Radiation Sciences
PSP Element(s) G-501300-001
DOI 10.1088/1361-6560/acaf45
WOS ID 000989524600001
Scopus ID 85151782413
PubMed ID 36584393
Erfassungsdatum 2023-11-30
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