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GLP-1-Mimetika – wegweisend zur Behandlung von Diabetes und Adipositas.

GLP-1 mimetics - pioneering for the treatment of diabetes and obesity.

BioSpektrum 29, 137-139 (2023)
Publ. Version/Full Text DOI
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Most obese patients would benefit from 5–10 % of weight loss but fail when using non-surgical approaches. The recent development of two anti-obesity drugs may change that therapeutic gap. Patients receiving long-acting glucagon-like peptide 1 (GLP1) agonist semaglutide achieve weight loss above 10 %. With tirzepatide, a co-agonist for GLP-1 and the gastric inhibitory polypeptide (GIP) receptor, more than 50 % of the patients even lose above 20 %, which rivals the efficacy of surgical interventions.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0947-0867
e-ISSN 1868-6249
Journal BioSpektrum
Quellenangaben Volume: 29, Issue: 2, Pages: 137-139 Article Number: , Supplement: ,
Publisher Springer
Non-patent literature Publications
Reviewing status Peer reviewed