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Open Access Green as soon as Postprint is submitted to ZB.
Astrocytic GABA in LHA is an obesity ‘thermostat’.
Nat. Metab. 5, 1454-1455 (2023)
Sa et al. identified a distinct neuronal subpopulation that controls brown adipose tissue thermogenesis. In mice fed a high-fat diet, hypothalamic GABRA5 neurons are deactivated by GABA released by surrounding astrocytes and inhibition of GABA synthesis ameliorates diet-induced obesity.
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Publication type
Article: Journal article
Document type
Editorial
Keywords
Lateral Hypothalamus
ISSN (print) / ISBN
2522-5812
e-ISSN
2522-5812
Journal
Nature metabolism
Quellenangaben
Volume: 5,
Issue: 9,
Pages: 1454-1455
Publisher
Springer
Publishing Place
London
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Obesity (IDO)
Grants
European Research Council (ERC)
Ministerio de Ciencia e Innovacion of Spain
Helmholtz Association - Initiative and Networking Fund
German Research Foundation (DFG)
Ministerio de Ciencia e Innovacion of Spain
Helmholtz Association - Initiative and Networking Fund
German Research Foundation (DFG)